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Epilepsy Research and Treatment
Volume 2012 (2012), Article ID 135364, 5 pages
http://dx.doi.org/10.1155/2012/135364
Research Article

Changing Global Trends in Seizure Outcomes Following Resective Surgery for Tuberous Sclerosis in Children with Medically Intractable Epilepsy

1Division of Neurosurgery, Department of Surgery, University of Toronto, Toronto, ON, Canada
2Institute of Medical Sciences, University of Toronto, Toronto, ON, Canada
3Hospital for Sick Children Research Institute, Suite 1503, 555 University Avenue, Toronto, ON, Canada M5G 1X8
4Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, ON, Canada
5Department of Neurology, Hospital for Sick Children, Toronto, ON, Canada

Received 9 September 2012; Accepted 30 October 2012

Academic Editor: Raidah S. Albaradie

Copyright © 2012 George M. Ibrahim et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. P. Curatolo, R. Bombardieri, and S. Jozwiak, “Tuberous sclerosis,” The Lancet, vol. 372, no. 9639, pp. 657–668, 2008. View at Publisher · View at Google Scholar · View at Scopus
  2. L. Hallett, T. Foster, Z. Liu, M. Blieden, and J. Valentim, “Burden of disease and unmet needs in tuberous sclerosis complex with neurological manifestations: systematic review,” Current Medical Research and Opinion, vol. 27, no. 8, pp. 1571–1583, 2011. View at Publisher · View at Google Scholar · View at Scopus
  3. F. E. Jansen, G. Huiskamp, A. C. van Huffelen et al., “Identification of the epileptogenic tuber in patients with tuberous sclerosis: a comparison of high-resolution EEG and MEG,” Epilepsia, vol. 47, no. 1, pp. 108–114, 2006. View at Publisher · View at Google Scholar · View at Scopus
  4. M. S. Aboian, L. C. Wong-Kisiel, M. Rank, N. M. Wetjen, E. C. Wirrell, and R. J. Witte, “SISCOM in children with tuberous sclerosis complex-related epilepsy,” Pediatric Neurology, vol. 45, no. 2, pp. 83–88, 2011. View at Publisher · View at Google Scholar · View at Scopus
  5. M. Karenfort, B. Kruse, H. Freitag, H. Pannek, and I. Tuxhorn, “Epilepsy surgery outcome in children with focal epilepsy due to tuberous sclerosis complex,” Neuropediatrics, vol. 33, no. 5, pp. 255–261, 2002. View at Publisher · View at Google Scholar · View at Scopus
  6. J. Roth, A. Olasunkanmi, W. S. Macallister et al., “Quality of life following epilepsy surgery for children with tuberous sclerosis complex,” Epilepsy and Behavior, vol. 20, no. 3, pp. 561–565, 2011. View at Publisher · View at Google Scholar · View at Scopus
  7. F. E. Jansen, K. P. J. Braun, O. van Nieuwenhuizen et al., “Diffusion-weighted magnetic resonance imaging and identification of the epileptogenic tuber in patients with tuberous sclerosis,” Archives of Neurology, vol. 60, no. 11, pp. 1580–1584, 2003. View at Publisher · View at Google Scholar · View at Scopus
  8. P. S. Chandra, N. Salamon, J. Huang et al., “FDG-PET/MRI coregistration and diffusion-tensor imaging distinguish epileptogenic tubers and cortex in patients with tuberous sclerosis complex: a preliminary report,” Epilepsia, vol. 47, no. 9, pp. 1543–1549, 2006. View at Publisher · View at Google Scholar · View at Scopus
  9. D. C. Chugani, H. T. Chugani, O. Muzik et al., “Imaging epileptogenic tubers in children with tuberous sclerosis complex using α-[11C]methyl-L-tryptophan positron emission tomography,” Annals of Neurology, vol. 44, no. 6, pp. 858–866, 1998. View at Scopus
  10. J. Y. Wu, N. Salamon, H. E. Kirsch et al., “Noninvasive testing, early surgery, and seizure freedom in tuberous sclerosis complex,” Neurology, vol. 74, no. 5, pp. 392–398, 2010. View at Publisher · View at Google Scholar · View at Scopus
  11. A. S. Harvey, J. H. Cross, S. Shinnar, G. W. Mathern, and ILAE Pediatric Epilepsy Surgery Survey Taskforce, “Defining the spectrum of international practice in pediatric epilepsy surgery patients,” Epilepsia, vol. 49, no. 1, pp. 146–155, 2008. View at Publisher · View at Google Scholar · View at Scopus
  12. G. M. Ibrahim, B. W. Barry, A. Fallah et al., “Inequities in access to pediatric epilepsy surgery: a bioethical framework,” Neurosurgical Focus, vol. 32, no. 3, article E2, 2012. View at Publisher · View at Google Scholar · View at Scopus
  13. L. Morgenstern, “Warning! Dangerous curve ahead: the learning curve,” Surgical Innovation, vol. 12, no. 1, pp. 101–103, 2005. View at Publisher · View at Google Scholar · View at Scopus
  14. G. M. Ibrahim, A. Fallah, O. C. Snead 3rd, J. Drake, J. T. Rutka, and M. Bernstein, “The use of high frequency oscillations to guide neocortical resections in children with medically-intractable epilepsy: how do we ethically apply surgical innovations to patient care?” Seizure, vol. 21, no. 10, pp. 743–747, 2012. View at Publisher · View at Google Scholar
  15. S. Goldring, “A method for surgical management of focal epilepsy, especially as it relates to children,” Journal of Neurosurgery, vol. 49, no. 3, pp. 344–356, 1978. View at Scopus
  16. G. L. Holmes and Y. Ben-Ari, “Seizures in the developing brain: perhaps not so benign after all,” Neuron, vol. 21, no. 6, pp. 1231–1234, 1998. View at Publisher · View at Google Scholar · View at Scopus
  17. K. J. Meador, “Cognitive outcomes and predictive factors in epilepsy,” Neurology, vol. 58, no. 8, supplement 5, pp. S21–S26, 2002. View at Scopus
  18. G. M. Ibrahim, A. Fallah, O. C. Snead 3rd et al., “Ethical issues in surgical decision making concerning children with medically intractable epilepsy,” Epilepsy and Behavior, vol. 22, no. 2, pp. 154–157, 2011. View at Publisher · View at Google Scholar · View at Scopus
  19. C. Helmstaedter and C. E. Elger, “Chronic temporal lobe epilepsy: a neurodevelopmental or progressively dementing disease?” Brain, vol. 132, no. 10, pp. 2822–2830, 2009. View at Publisher · View at Google Scholar · View at Scopus
  20. R. Jonas, S. Nguyen, B. Hu et al., “Cerebral hemispherectomy: hospital course, seizure, developmental, language, and motor outcomes,” Neurology, vol. 62, no. 10, pp. 1712–1721, 2004. View at Scopus
  21. P. Perot, B. Weir, and T. Rasmussen, “Tuberous sclerosis: surgical therapy for seizures,” Archives of Neurology, vol. 15, no. 5, pp. 498–506, 1966. View at Scopus
  22. E. M. Bebin, P. J. Kelly, M. R. Gomez, P. Genton, and C. K. Benninger, “Surgical treatment for epilepsy in cerebral tuberous sclerosis,” Epilepsia, vol. 34, no. 4, pp. 651–657, 1993. View at Scopus
  23. A. M. Avellino, M. S. Berger, R. C. Rostomily, C. M. Shaw, and G. A. Ojemann, “Surgical management and seizure outcome in patients with tuberous sclerosis,” Journal of Neurosurgery, vol. 87, no. 3, pp. 391–396, 1997. View at Scopus
  24. J. E. Baumgartner, J. W. Wheless, S. Kulkarni et al., “On the surgical treatment of refractory epilepsy in tuberous sclerosis complex,” Pediatric Neurosurgery, vol. 27, no. 6, pp. 311–318, 1997. View at Scopus
  25. M. M. Guerreiro, F. Andermann, E. Andermann et al., “Surgical treatment of epilepsy in tuberous sclerosis: strategies and results in 18 patients,” Neurology, vol. 51, no. 5, pp. 1263–1269, 1998. View at Scopus
  26. E. Asano, D. C. Chugani, O. Muzik et al., “Multimodality imaging for improved detection of epileptogenic foci in tuberous sclerosis complex,” Neurology, vol. 54, no. 10, pp. 1976–1984, 2000. View at Scopus
  27. S. Koh, P. Jayakar, C. Dunoyer et al., “Epilepsy surgery in children with tuberous sclerosis complex: presurgical evaluation and outcome,” Epilepsia, vol. 41, no. 9, pp. 1206–1213, 2000. View at Scopus
  28. K. Kagawa, D. C. Chugani, E. Asano et al., “Epilepsy surgery outcome in children with tuberous sclerosis complex evaluated with α-[11C]methyl-L-tryptophan positron emission tomography (PET),” Journal of Child Neurology, vol. 20, no. 5, pp. 429–438, 2005. View at Scopus
  29. D. K. Lachhwani, E. Pestana, A. Gupta, P. Kotagal, W. Bingaman, and E. Wyllie, “Identification of candidates for epilepsy surgery in patients with tuberous sclerosis,” Neurology, vol. 64, no. 9, pp. 1651–1654, 2005. View at Publisher · View at Google Scholar · View at Scopus
  30. T. Kamimura, J. Tohyama, M. Oishi et al., “Magnetoencephalography in patients with tuberous sclerosis and localization-related epilepsy,” Epilepsia, vol. 47, no. 6, pp. 991–997, 2006. View at Publisher · View at Google Scholar · View at Scopus
  31. H. L. Weiner, C. Carlson, E. B. Ridgway et al., “Epilepsy surgery in young children with tuberous sclerosis: results of a novel approach,” Pediatrics, vol. 117, no. 5, pp. 1494–1502, 2006. View at Publisher · View at Google Scholar · View at Scopus
  32. F. E. Jansen, A. C. van Huffelen, P. C. van Rijen et al., “Epilepsy surgery in tuberous sclerosis: the Dutch experience,” Seizure, vol. 16, no. 5, pp. 445–453, 2007. View at Publisher · View at Google Scholar · View at Scopus
  33. F. Teutonico, R. Mai, O. Devinsky et al., “Epilepsy surgery in tuberous sclerosis complex: early predictive elements and outcome,” Child's Nervous System, vol. 24, no. 12, pp. 1437–1445, 2008. View at Publisher · View at Google Scholar · View at Scopus
  34. P. Major, S. Rakowski, M. V. Simon et al., “Are cortical tubers epileptogenic? Evidence from electrocorticography,” Epilepsia, vol. 50, no. 1, pp. 147–154, 2009. View at Publisher · View at Google Scholar · View at Scopus
  35. J. L. Wen, J. X. Liao, L. Chen et al., “Follow-up of tuberous sclerosis complex complicated by epilepsy in children,” Chinese Journal of Contemporary Pediatrics, vol. 11, no. 12, pp. 996–998, 2009. View at Scopus
  36. A. van der Heide, A. C. van Huffelen, W. P. J. Spetgens, C. H. Ferrier, O. van Nieuwenhuizen, and F. E. Jansen, “Identification of the epileptogenic zone in patients with tuberous sclerosis: concordance of interictal and ictal epileptiform activity,” Clinical Neurophysiology, vol. 121, no. 6, pp. 842–847, 2010. View at Publisher · View at Google Scholar · View at Scopus
  37. S. Liang, A. Li, M. Zhao et al., “Epilepsy surgery in tuberous sclerosis complex: emphasis on surgical candidate and neuropsychology,” Epilepsia, vol. 51, no. 11, pp. 2316–2321, 2010. View at Publisher · View at Google Scholar · View at Scopus