Review Article

Neuropathology of Temporal Lobe Epilepsy

Table 1

International league against epilepsy consensus classification system for focal cortical dysplasia (FCD) [34].

FCD type I: isolatedFCD Ia: abnormal radial cortical laminationFCD Ib: abnormal tangential cortical laminationFCD Ic: abnormal radial and tangential cortical lamination

FCD type II: isolatedFCD IIa: dysmorphic neuronsFCD IIb: dysmorphic neurons and balloon cells

FCD type III: associated with principal lesionFCD IIIa: cortical lamination abnormalities in the temporal lobe associated with hippocampal sclerosisFCD IIIb: cortical lamination abnormalities adjacent to a glial or glioneuronal tumorFCD IIIc: cortical lamination abnormalities adjacent to vascular malformationFCD IIId: cortical lamination abnormalities adjacent to any other lesion acquired during early life (e.g., trauma, ischemic injury, and encephalitis)