This 2-year-old girl had onset of infantile spasms at the age 6 months, which were refractory to three antiepileptic medications. During the clusters of spasms, she had head drops, nonforced head turn, and eye deviation to the right, with elevation of both upper extremities. Her EEG (a) shows a generalized sharp wave followed by high frequency and low-amplitude activity during the spasm (50 microvolts/mm, 30 mm/sec). Her coronal FLAIR MRI (b) shows a lesion in the right temporal region, which was found to be a ganglioglioma. She has remained seizure-free since surgery.
