Review Article

Continuous Spikes and Waves during Sleep: Electroclinical Presentation and Suggestions for Management

Figure 1

Different values in the quantification of the epileptiform activity result when using different methods of quantification. Epileptiform activity appears much more frequently in (b) than in (a). Both tracings have a 100% of epileptiform activity if the reader quantifies the epileptiform activity using spike percentage, that is, counting the percentage of 1-second bins occupied by spike-waves. However, if the reader quantifies the epileptiform activity using spike frequency, that is, the total number of individual spike-waves per unit of time (per 10 seconds in this page, per 100 seconds in a longer tracing), epileptiform activity is almost double in (b) than in (a). Note that the tracings have different voltage gains.
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(a)
583531.fig.001b
(b)