Temporal Lobe Resective Surgery for Medically Intractable Epilepsy: A Review of Complications and Side Effects

Table 1

Synopsis of data of pediatric temporal lobe epilepsy surgical series and their reported complications.

Series/year of publication	Study characteristics	Number of pts	Surgical procedure	Mortality	Mean; followup	Seizure-free; outcome	Complications	Cumulative complication rate*	Behavioral/cognitive/psychiatric; complications
Erba et al.,; 1992 [18]	Prospective, pediatric & adolescent	46	Standard ATL + AH	0%	5 years	85%	Infection: 2.1%; Hemiparesis/hemianopsia: 4.3%; C.N. Palsy: 2.1%	17.1%	Depression: 4.3%; Behavioral syndrome: 4.3%
Sinclair et al.,; 2003 [19]	Retrospective, pediatric	32	Standard ATL	0%	6.9 years	76%	Infection: 3.1%; Hydrocephalus: 3.1%; Stroke: 3.1%	9.3%	N/A
Terra-Bustamante et al.,; 2005 [20]	Prospective, pediatric & adolescent	35	Standard ATL + AH	0%	3.5 years	77.1%	Hemianopsia: 2.9%	2.9%	N/A
Kim et al.,; 2008 [9]	Prospective, pediatric	59	Standard ATL + AH	0%	62.3 months	69%	VFDs: 22.0%; Hemiparesis: 8.5%; Wound infection: 8.5%; Meningitis: 3.4%	47.5%	Psychosis: 5.1%
Lopez-Gonzalez et al.,; 2012 [6]	Retrospective, pediatric	130	Cortico-amygdalo-hippocampectomy (CAH),; Lesionectomy + CAH,; Lesionectomy,; neocortical resection,; tailored ATL + AH,; selective AH	0%	2 years	72%	VFDs: 1.5%; Transient speech Difficulties: 0.7%; Infection: 1.5%	17%	Depression: 10%
Vadera et al.,; 2012 [13]	Retrospective, pediatric	45	Standard ATL + AH	0%	60.2 months	69%	None	0%	N/A

∗This rate includes the behavioral/cognitive/psychiatric complications. ATL: anterior temporal lobectomy; AH: amygdalohippocampectomy; VFDs: visual field deficits; C.N.: cranial nerve.