Why Are Seizures Rare in Rapid Eye Movement Sleep? Review of the Frequency of Seizures in Different Sleep Stages

Table 5

Relative focal interictal discharge rates.

Paper/sleep stage	W	N1	N2	N3	REM
Clemens et al. 2005 [65]	1.52	2.50	1.85	2.67	1.00
Clemens et al. 2003 [66]	0.41	1.56	1.48	2.46	1.00
Ferillo et al. 2000 [67]		0.91	1.09	1.81	1.00
Malow et al. 1998 [68]		2.45	3.79	7.39	1.00
Malow et al. 1997 [69]		2.38	4.50	7.13	1.00
Billiard et al. 1981 [70]—Symptomatic	0.84	1.68	1.68	1.68	1.00
Billiard et al. 1981 [70]—Definite	0.70	1.43	1.43	1.43	1.00
Autret et al. 1987 [47]/1997 [48]	0.44	1.18	1.18	1.15	1.00
Rossi et al. 1984 [71, 72]*	1.17	1.33	1.33	1.18	1.00
Montplaisir et al. 1982 [73]*	1.21		2.43		1.00
Weighted mean	1.11	1.75	1.69	2.46	1.00

∗Intracranial depth electrode study.