Both Maternal and Pup Genotype Influence Ultrasonic Vocalizations and Early Developmental Milestones in Tsc2^+/− Mice

Figure 4

WT and Tsc2 heterozygous pups born to WT or Tsc2 heterozygous mothers display differences in overall number of calls dependent on pup genotype. (a) Heterozygous pups from WT mothers have delayed peak number of vocalizations. (b) WT and heterozygous pups from Tsc2 heterozygous mothers show no significant differences in number of calls; although not statistically relevant, heterozygous pups have delayed peak number of calls. ^∗∗𝑃<0.005.

(a)

(b)