Hippocampography Guides Consistent Mesial Resections in Neocortical Temporal Lobe Epilepsy
Table 2
Group characteristics.
Mesial ECoG (EHG-guided hippocampectomy)
Lateral ECoG (unguided hippocampectomy)
Group differences p (univariate)
Association with Engel I p (univariate)
Primary outcome
Hippocampectomy variability (deviation from mean, cm)
0.7 (0.2–2.3)
1.8 (0.6–4.9)
0.01
n/a
Secondary outcomes
Absolute hippocampectomy length (cm)
2.2 (1–4.5)
3.1 (0.5–8)
0.20
0.74
Engel Class I
12 (86%)
5 (42%)
0.02
n/a
Possible confounders of secondary outcome Engel Class I
Age
31.8 (7–66)
37.8 (18–74)
0.36
0.64
Male gender
8 (57%)
6 (50%)
0.72
0.48
Comorbid MTS
6 (43%)
6 (50%)
0.72
0.34
NTLE+M
7 (50%)
1 (8%)
0.051
0.02
NTLE+E
1 (7%)
3 (25%)
0.07
0.96
NTLE+M+E
1 (7%)
5 (42%)
0.002
0.046
Follow-up duration
1.7 (0.03–4.22)
2.1 (0.03–4.63)
0.40
0.07
Statistically significant on univariate analysis. Statistically significant on multivariate analysis: NTLE+M was positively associated with Engel I; NTLE+M+E was negatively associated against Engel I. NTLE+M: neocortical temporal lobe epileptogenic lesion with mesial temporal invasion; NTLE+E: neocortical temporal lobe epileptogenic lesion with extratemporal invasion; NTLE+M+E: neocortical temporal lobe epileptogenic lesion with mesial temporal and extratemporal invasion; n/a: not applicable.