RNA Polymerase II Elongation at the Crossroads of Transcription and Alternative Splicing

<table>Promoters affect alternative splicing. <i>α</i>-globin/FN hybrid minigenes under the control of different promoters, used in transient transfections of mammalian cells in culture to assess inclusion levels of the alternatively spliced E33 (EDI or EDA) cassette exon (dark yellow). Inclusion level with the FN promoter is &gt;10-fold higher when compared to the <i>α</i>-globin promoter.</table>

Genetics Research International

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Figure 1

Figure 1: RNA Polymerase II Elongation at the Crossroads of Transcription and Alternative Splicing 