Epigenetics in Friedreich's Ataxia: Challenges and Opportunities for Therapy
Figure 1
The position of DNA methylation and CTCF binding sites within TNR expansion loci. (a) FRAXA, (b) DM1, (c) SCA7, and (d) FRDA. Grey boxes represent regions of disease-associated DNA methylation. Arrow marks represent the direction of transcription. Red triangles indicate the position of repeats. This image was adapted from [139].