Association of Polymorphisms of Phase I Metabolizing Genes with Sister Chromatid Exchanges in Occupational Workers Exposed to Toluene Used in Paint Thinners

Table 3

Influence of CYP genotypes on SCE frequency.

Genotype	SCE/cell (mean ± SD)
	Number ()	Control	Number ()	Exposed
CYP1A1m2
wt/wt	23	1.66 ± 0.76	16	4.27 ± 0.73
wt/mt	6	1.89 ± 0.55	10	5.36 ± 0.74
mt/mt	1	2.36 ± 0.00	4	5.61 ± 0.66
CYP2E1
wt/wt	25	1.73 ± 0.54	10	4.31 ± 0.64
wt/mt	4	1.88 ± 0.45	16	4.80 ± 0.87
mt/mt	1	1.01 ± 0.00	4	6.11 ± 0.08

Significant at ; multivariate ANOVA test was used for the comparison in SCE frequency in multiple subgroups among studied population.