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Genetics in Genomic Era

Call for Papers

The last decade has been known as the “genomic era.” Whole genome and exome next-generation sequencing provide us with a new arsenal of tools with which to study human and animal genetics. It is now possible to identify genetic mutations that cause the Mendelian disease even when the number of affected individuals (in rare and neglected diseases) is very limited. This has been facilitated by the availability of large quantities of genome sequence data from the general population (1000 Genomes Project). Genomic data analysis should be useful in dissecting the mechanisms underlying complex polygenic disease. Even though we possess new capabilities, we are also encountering a new set of problems with analysis of genomic data and reanalysis of already published (deposited in databases) data. The problems of genomic data presentation, format, integration, sharing, and reanalysis are now starting to be addressed.

We invite authors to submit original research articles as well as reviews that would present state of the art in the field of human, animal, and plant genetics using the latest genomic tools. Potential topics include, but are not limited to:

  • Organization of genetic networks and enzymatic pathways and their contribution to cellular and organismal phenotypes
  • Structural and functional components encoded in genomes
  • Analysis of the heritable variation in genomes
  • Strategies for identifying the genetic contributions to disease and the drug response
  • Evolutionary variation across species and the underlying mechanisms responsible
  • Genome instability and mutagenesis in plant genomes
  • Genome-based approaches to the prediction of disease susceptibility and drug response, presymptomatic detection of illness, and molecular taxonomy of disease states
  • Using new understanding of genes and pathways to develop powerful new therapeutic approaches to disease
  • Options for the ethically responsible use of human genomic data in medical and nonmedical settings

Before submission authors should carefully read over the journal’s Author Guidelines, which are located at http://www.hindawi.com/journals/gri/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/submit/journals/gri/era according to the following timetable:

Manuscript DueFriday, 1 August 2014
First Round of ReviewsFriday, 24 October 2014
Publication DateFriday, 19 December 2014

Lead Guest Editor

Guest Editors

  • David N. Cooper, Institute of Medical Genetics, School of Medicine, Cardiff University, Cardiff CF14 4XN, UK
  • Elena Stepchenkova, Saint-Petersburg Branch of N. I. Vavilov Institute of General Genetics, Russian Academy of Sciences, Saint Petersburg 199034, Russia
  • Igor B. Rogozin, NCBI, NLM, NIH, Bethesda, MD 20894, USA