Liver Regeneration after Partial Hepatectomy Is Not Impaired in Mice with Double Deficiency of Myd88 and IFNAR Genes
Figure 4
Impact of preexisting liver lesions on hepatocyte proliferation after partial hepatectomy (PH) in Myd88-IFNAR double-KO mice. The graphs show (a) the mean number of BrdU-labeled hepatocytes and (b) the total number of mitotic figures in hepatocytes, counted in eight 200x microscopic fields per mouse liver at the indicated times after PH or sham laparotomy in Myd88-IFNAR double-KO mice without (black bars) and with (hatched bars) preexisting liver lesions. The number of mice in each group is indicated below the -axis. The dataset for Myd88-IFNAR double-KO mice without preexisting liver lesions is the same as that shown in Figure 3. The small sample size precludes a formal statistical analysis.
