Table 1: Factors affecting QOL in patients with IBD.

FactorStudyResult

Disease-related factorsDisease activityVidal et al. [74]Disease activity was one of strongest predictors of QOL impairments.
Albersnagel and Dijkstra [72]Disease activity adversely affects QOL of the patients.
Haapamaki [71]Disease activity was the most factors related to QOL impairment.
Graff et al. [73]Patients with active disease had poorer QOL scores, but participants with either active or inactive disease had suboptimal general QOL.
Disease severityGuthrie et al. [58]Disease severity was one of factors contributed to impaired QOL.
Disease typeMikocka-Walus et al. [40]CD patients tended to have poorer physical QOL than UC patients.
Casellas et al. [70]Disease type did not predict QOL scores.
Guthrie et al. [58]After controlling disease severity, there were no significant differences between CD and UC in QOL scores.
Graff et al. [73]Disease type was not contributor to QOL.
History of surgeryHaapamaki [71]Lower QOL scores were seen in those patients with a history of surgery.
Disease chronicityHaapamaki [71]Lower QOL scores were seen in newly diagnosed patients.
Casellas et al. [70]Longer disease duration and lower recurrence/year index predicted a better QOL.
Need for hospitalizationCasellas et al. [70]Nonnecessity of hospitalization predicted a better QOL.

Demographic factorsGenderHaapamaki [71]Female had poorer QOL than men.
Casellas et al. [70]Female gender predicted a better QOL.
AgeHaapamaki [71]Older age patients had poorer QOL.
Educational levelCasellas et al. [70]Higher level of education predicted a better QOL.

Psychological factorsPersonalityVidal et al. [74]Personality traits did not play a significant role in QOL.
Moreno-Jiménez et al. [44]Neuroticism and greater difficulty in describing feelings to others were related to poorer QOL.
Psychological distressVidal et al. [74]Psychological distress was one of strongest predictors of QOL impairments.
Guthrie et al. [58]Psychological symptoms were one of factors contributed to impaired QOL.
Social supportMoradkhani [76]Activity in online support groups was not related to QOL.