Effect of Ursodeoxycholic Acid Alone and Ursodeoxycholic Acid Plus Domperidone on Radiolucent Gallstones and Gallbladder Contractility in Humans

Table 3

Characterisitcs of patients in treatment groups in pre- and posttreatment*.

Parameters	UDCA alone			UDCA and domperidone
	Pretreatment	Posttreatment	P	Pretreatment	Posttreatment	P
BMI (kg/m^2)	29.0±4	28.8±6	NS	27.1±3	27.1±5	NS
Glucose (mg/dL)	90.5±11	96±6	NS	99.1±20	88±13	NS
Cholesterol (mg/dL)	182.4±34	178±36	NS	186.1±30	178±59	NS
HDL-Cholesterol (mg/dL)	49.7±16	51.2±9	NS	53.5±17	56.7±10.6	NS
LDL-Cholesterol (mg/dL)	105.0±35	105±42	NS	104.3±51	101±56	NS
Triglyceride (mg/dL)	136.5±75	142±52	NS	157.4±90	178±49	NS
Solitary stone	6	5	NS	4	4	NS
Multiple stone	16	8	NS	14	7	NS
FGVav (mL)	26.6±9.6	27.0±5.2	NS	27.8±13.4	29.2±6.4	NS
RGVav (mL)	7.0±3	6.5±2.6	NS	7.8±5	7.8±3.7	NS
EFav (%)	73.6±15	75.9±16	NS	71.9±19	73.2±14	NS

*Results are expressed as mean ± SD.
BMI: body mass index; FGV_av: average fasting gallbladder volume; RGV_av: average residual gallbladder volume; EF_av: average ejection fraction.
NS: not significant.