Table 2:
Comparison of perioperative variables between 34 patients treated with neoadjuvant chemotherapy prior to cytoreductive surgery and HIPEC and 24 patients that did not receive preoperative chemotherapy before cytoreductive surgery and HIPEC.
Clinical characteristic
Patients with PMCA from appendix cancer
Neoadjuvant chemotherapy
No neoadjuvant chemotherapy
P
value
Number of patients
34
24
Peritoneal cancer index (mean)
19
28
0.0003
Number of peritonectomies
0.0032
Mean
2.3
3.7
Range
0–5
1–5
Number of visceral resections
<0.001
Mean
2.7
4.4
Range
1–5
2–7
Completeness of cytoreduction
0.78
CCR 0/CCR 1
22
12
CCR 2
7
5
CCR 3
5
5
Complications
0.16
None or grade1/2
8
10
Grade 3 or 4
26
14