Usefulness of Noninvasive Predictors of Oesophageal Varices in Black African Cirrhotic Patients in Côte d'Ivoire (West Africa)

Table 1

Characteristics of cirrhotic patients of the training and validation samples.

	Training sample				Validation sample (n = 91)
	All (n = 111)	NOV (n = 26)	OV (n = 85)	P value
Age (years) [median (range)]	49 (62)	52 (52)	49.5 (63)	0.3	50 (59)
Sex (female) [n (%)]	33 (29.7)	14 (56)	19 (22.4)	0.002	35 (38.5)
Collateral venous circulation [n (%)]	24 (21.6)	4 (15.4)	20 (23.5)	0.3	5 (5.5)
Clinical ascites [n (%)]	84 (75.7)	21 (80.8)	63 (74.1)	0.3	66 (72.5)
Total bilirubin (mg/dL) [median (range)]	17.8 (247)	13 (248)	14 (234)	0.9	7 (247)
Prothrombin time (%) [median (range)]	55 (86)	67 (82)	56 (86)	0.2	64 (79)
Albumin (g/L) [median (range)]	26 (37)	25 (29)	25 (34)	0.3	22 (25)
Platelet count (×10^3/mL) [median (range)]	930 (404)	146 (491)	90 (553)	0.0001	113 (553)
Spleen diameter (mm) [median (range)]	139 (123)	110 (123)	136 (124)	0.002	101 (123)
Portal vein diameter (mm) [median (range)]	12.8 (14)	11.8 (7)	12 (14)	0.8	10 (8)
PC/SD ratio [median (range)]	651.5 (2523)	1390 (4921.2)	642.8 (5530)	0.0001	880 (5530)
Child-Pugh score [n (%)]				0.4
A	25 (22.5)	4 (15.4)	21 (24.7)		18 (19.8)
B	39 (35.1)	12 (46.2)	27 (31.8)		48 (52.7)
C	47 (42.3)	10 (38.5)	37 (43.5)		20 (22.0)
Oesophageal varices [n (%)]
No varices	26 (23.4)	—	—		19 (20.9)
Stage 1	7 (6.3)	—	—		12 (13.2)
Stage 2	54 (48.6)	—	—		34 (37.4)
Stage 3	24 (21.6)	—	—		26 (28.6)
Aetiologies of cirrhosis [n (%)]^a				0.3
HBV	68 (61.3)	16 (61.5)	52 (61.2)		53 (58.2)
HCV	14 (12.6)	4 (15.4)	10 (11.8)		14 (15.4)
HBV + HCV coinfection	2 (1.8)	0	2 (20)		—
Alcohol	23 (20.7)	6 (23.1)	17 (20)		24 (26.4)
Mixed (viral and alcohol)	4 (3.6)	0	4 (4.7)		—

NOV: no oesophageal varices, OV: oesophageal varices, PC/SD ratio: platelet count-spleen diameter ratio, HBV: hepatitis B virus, HCV: hepatitis C virus
^aAetiologies were grouped in 2 classes: viral and others (viral and/or alcohol).