Table 4: Studies of molecular biologic diagnosis of pancreatic carcinoma using specimens obtained by EUS-FNA.

Biological analyses
AuthorYearEUS-FNA samplesSensitivitySpecificityPositive predictive valueNegative positive valueAccuracyDiagnosis

Reicher et al. [11]20114687.9%93.8%96.7%78.9%89.8%Combination with cytology and FISH
KRAS Bournet et al. [10]200917888.0%100%100%63.0%90.0%Combination with cytopathology
Maluf-Filho et al. [8]20077490.9%47.6%89.5%98.1%89.2%Combination with cytopathology

P53Jahng et al. [17]20106151.0%100%Combination with cytology
Itoi et al. [16]20056290.0%91.0%92%Combination with cytopathology

P16Salek et al. [20]200710185.0%100.0%Monitoring the loss of heterozygosity
SMAD4Salek et al. [20]200710178.0%57.0%Monitoring the loss of heterozygosity

MUCsWang et al. [26]200740100%91.1%MUC5AC+cytology
Giorgadze et al. [25]20063070%100% 100% 100%75%Combination of MUC1+/ MUC2−/ MUC5AC+

S100PKosarac et al. [34]20111478.2%87.5%
Daniel et al. [35]20116290.0%67.0%

*FISH: fluorescense in situ hybridization.