Research Article

Drugs and Constipation in Elderly in Nursing Homes: What Is the Relation?

Table 1

Characteristics of the participants and comparisons between participants with and without constipation. The results are given as mean (standard deviation (SD)), median (range), and number (proportion (%)).

Characteristics1All participants Participants with constipation Participants without constipation Statistics value

Age (years)85.4 (SD 7.1)85.3 (SD 6.9)85.6(SD 7.5)0.69
Gender (female)188 (70.4%)139 (72.8%)49 (64.5%)0.19
Ability to give informed consent 98 (36.7%)66 (34.6%)32 (42.1%)0.26
Functional constipation (Rome III) ( ) 95 (35.7%)95 (50.0%)20n.a.
Body mass index (kg/m2) ( )25.5 (SD 4.9)24.5 (SD 5.3)24.7 (SD 4.9)0.72
Smoking ( )19/49/19513/30/1446/19/51
 Current/before/never(7.2/18.6/74.1%)(7.0/16.0/77.0%)(7.9/25.0/67.1%)0.22
Use of alcohol > once a month ( )39 (14.6%)28 (14.9%)11 (14.7%)1.00
Walking steps/day ( )200 (0–5000)139 (0–5000)400 (0–5000)0.02
Mobility120/80/67100/48/4320/32/24
 Bedridden/walk indoors/walk outdoors(44.9/30.0/25.1%)(52.4/25.1/22.5%)(26.3/42.1/31.6%)<0.01
Intake of fluids (Glass/day)9.9 (SD 2.9)9.0 (SD 2.8)10.1 (SD 3.0)<0.01
Dietary fibre (gram/day)15.6 (SD 6.4)15.3 (SD 6.3)16.4 (SD 6.6)0.18
Katz’ Activity of Daily Living 3 ( )2 (0–6)1 (0–6)3 (0–6)<0.001
Mini Nutritional Assessment score ( )21.4 (SD 3.5)19.6 (SD 3.9)21.5 (SD 3.6)0.001
Type of food ( )41/44/18133/36/1218/8/60
Mashed/without crust/ordinary food(15.4/16.5/67.8%)(17.4/18.9/63.7%)(10.5/10.5/78.9%)0.04
Incontinence urine only ( )93 (35.0%)73 (38.2%)20 (26.7%)0.09
Incontinence urine and faeces ( )124 (46.8%)90 (47.4%)34 (45.3%)0.79
Bedsore/wound ( )32 (12.1%)28 (14.7%)4 (5.3%)0.04
Number of diseases ( )5 (1–15)5 (0–15)5 (0–10)0.85
Heart diseases ( )118 (44.5%)82 (43.2%)36 (48.0%)0.50
Venous thrombosis, pulmonary embolism ( )20 (7.6%)17 (8.9%)3 (4.1%)0.21
Stroke ( )91 (34.5%)72 (38.1%)19 (25.3%)0.06
Depression/anxiety ( )131 (49.2%)100 (52.4%)31 (41.3%)0.13
Dementia ( )148 (55.8%)105 (55.0%)43 (58.1%)0.68
Diabetes (both I and II) ( )32 (12.0%)20 (10.5%)12 (16.0%)0.22
Parkinson’s disease ( )15 (5.6%)10 (5.2%)5 (6.7%)0.77
Hypothyroidism ( )20 (7.5%)9 (4.7%)11 (6.7%)0.001
S-creatinine (above reference values) ( )62 (24.4%)37 (20.4%)25 (34.2%)0.02
Albumin (g/L) ( )38.9 (SD 4.1)38.5 (SD 4.2)39.5 (SD 3.7)0.16

1Number of residents is given in brackets when data are missing.
2 Use of laxatives regularly is included in the definition of constipation.
3 Katz Index of Independence in Activities of daily living. (Score 0–6: 0 = very dependent; 6 = independent).