Table 1: Molecular weight and area under the curve ratios of intraperitoneal exposure to systemic exposure of chemotherapeutic agents used to treat peritoneal carcinomatosis.

DrugMolecular weight (Daltons)Area under the curve ratio

5-Fluorouracil130.08250
Carboplatin371.2510
Cisplatin300.17.8
Docetaxel861.9552
Doxorubicin579.99230
Etoposide588.5865
Floxuridine246.275
Gemcitabine299.5500
Irinotecan677.19N/A
Melphalan305.293
Mitomycin C334.323.5
Mitoxantrone517.41115–255
Oxaliplatin397.316
Paclitaxel853.91000
Pemetrexed597.4940.8