Table 1: Molecular weight and area under the curve ratios of intraperitoneal exposure to systemic exposure of chemotherapeutic agents used to treat peritoneal carcinomatosis.

Drug Molecular weight (Daltons) Area under the curve ratio 5-Fluorouracil 130.08 250 Carboplatin 371.25 10 Cisplatin 300.1 7.8 Docetaxel 861.9 552 Doxorubicin 579.99 230 Etoposide 588.58 65 Floxuridine 246.2 75 Gemcitabine 299.5 500 Irinotecan 677.19 N/A Melphalan 305.2 93 Mitomycin C 334.3 23.5 Mitoxantrone 517.41 115–255 Oxaliplatin 397.3 16 Paclitaxel 853.9 1000 Pemetrexed 597.49 40.8