Research Article
Vitamin D Receptor Polymorphisms Predispose to Primary Biliary Cirrhosis and Severity of the Disease in Polish Population
Table 2
Distribution of VDR polymorphisms (rs1544410, rs7975232, rs731236) in PBC patients and controls subjects.
| | Genotype | PBC (%) | Controls (%) | | |
| | rs1544410 (BsmI) |
| | AA (BB) | 20 (14.0%) | 95 (31.1%) | 14.89 | 0.0001 | | GA (bB) | 75 (52.4%) | 135 (44.1%) | 2.49 | 0.096 | | GG (bb) | 48 (33.6%) | 76 (24.8%) | 3.71 | 0.054 |
| | rs7975232 (ApaI) |
| | TT (AA) | 40 (28%) | 75 (24.9%) | 0.61 | 0.43 | | GT (aA) | 80 (56%) | 161 (53.5%) | 0.43 | 0.51 | | GG (aa) | 23 (16%) | 65 (21.6%) | 1.64 | 0.41 |
| | rs731236 (TaqI) |
| | TT (TT) | 20 (16%) | 100 (33.2%) | 17.39 | <0.0001 | | TC (Tt) | 77 (53.8%) | 140 (54.5%) | 2.55 | 0.26 | | CC (tt) | 46 (30.2%) | 37 (12.3%) | 26.07 | <0.0001 |
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