Table 4: Clinical and laboratory data depending on analyzed polymorphisms.
(a)

ApaI (rs7975232)
AA (TT) aA (GT) aa (GG) P
(AA versus Aa)
P
(aa versus Aa)
P
(aa versus AA)

Gender (F/M)36/467/1320/30.40.90.7
Cirrhosis at Lbx (N/Y)20/834/2110/90.50.60.2
Advanced fibrosis stage III/IV on histology (N/Y)15/1128/278/100.60.30.5
Age of diagnosis (years) 0.80.40.3
AST (IU/mL) 0.40.40.2
ALT (IU/mL) 0.20.90.3
AP (IU/mL) 0.20.10.02
GGT (IU/mL) 0.10.90.2
Bilirubin (mg/dL) 0.90.30.4
Albumin (g/dL) 0.10.90.2
INR 0.10.10.9
Cholesterol (mg/dL) 0.40.70.8
TG (mg/dL) 0.20.80.5
Sp100 Ab34/462/1617/50.30.80.3
Gp210 Ab31/767/1121/10.60.30.2
AMA (Y/N)31/968/1219/40.30.70.7

(b)

BsmI (rs15444410)
bb (GG) bB (GA) BB (AA) P
(bb versus Bb)
P
(BB versus B)
P
(bb versus BB)

Gender (F/M)40/866/917/30.60.70.9
Cirrhosis at Lbx (N/Y)17/2238/139/30.0040.90.1
Advanced fibrosis stage III/IV on histology (N/Y)15/2330/206/50.10.70.5
Age of diagnosis (years) 0.20.10.4
AST (IU/mL) 0.050.90.2
ALT (IU/mL) 0.20.80.3
AP (IU/mL) 0.40.20.06
GGT (IU/mL) 0.20.30.7
Bilirubin (mg/dL) 0.50.50.8
Albumin (g/dL) 0.40.60.9
INR 0.20.40.9
Cholesterol (mg/dL) 0.80.40.5
TG (mg/dL) 0.60.20.4
Sp100 Ab35/1263/1015/30.10.70.5
Gp210 Ab41/662/1116/20.80.90.9
AMA (Y/N)40/863/1215/5>0.90.30.5

(c)

TaqI (rs731236)
TT (TT) Tt (TC) Tt (CC) P
(TT versus tT)
P
(tt versus tT)
P
(tt versus TT)

Gender (F/M)37/969/817/30.20.70.7
Cirrhosis at Lbx (N/Y)15/940/139/30.3>0.90.7
Advanced fibrosis Stage III/IV on histology (N/Y)13/2332/206/50.030.70.3
Age of diagnosis (years) 0.20.10.4
AST (IU/mL) 0.030.90.2
ALT (IU/mL) 0.20.90.3
AP (IU/mL) 0.40.20.06
GGT (IU/mL) 0.20.40.09
Bilirubin (mg/dL) 0.90.60.6
Albumin (g/dL) 0.40.60.9
INR 0.60.50.7
Cholesterol (mg/dL) 0.80.30.4
TG (mg/dL) 0.60.20.4
Sp100 Ab34/1164/1115/30.20.90.7
Gp210 Ab39/664/1116/20.90.90.9
AMA (Y/N)40/662/1516/40.5>0.90.5

Lbx: liver biopsy; AspAT: aspartate aminotransferase; AlAT: alanine aminotransferase; AP: alkaline phosphatase; GGT: gamma-glutamyl transferase; INR: international normalized ratio; TG: triglycerides, AMA: antimitochondrial antibodies.