Clinical Study

The Role of Serum Cytokines in the Pathogenesis of Hepatic Osteodystrophy in Male Cirrhotic Patients

Table 2

Lumbar and femur T-scores, cytokines, hormones and bone metabolism data* of the study population.

ParameterControlCirrhosisCirrhosis-viralCirrhosis-alcoholicAlcoholic

Lumbar T score−0.16 ± 0.97−0.29 ± 1.04−0.15 ± 0.97−0.50 ± 1.12−0.61 ± 1.54
Femur T Score0.18 ± 1.380.27 ± 1.070.35 ± 1.040.14 ± 1.130.13 ± 1.29
Interleukin 1 (ng/mL)15.1 ± 55.77.6 ± 28.311.1 ± 35.81.9 ± 2.92.0 ± 3.2
Interleukin 2 (ng/mL)1435 ± 4192623 ± 8752428 ± 6372931 ± 11111746 ± 458
Interleukin 6 (ng/mL)49.6 ± 123.273.9 ± 106.076.1 ± 129.770.3 ± 54.843.7 ± 72.6
Interleukin 8 (ng/ml)106.5 ± 148.6164.4 ± 169.3195.8 ± 203.2114.6 ± 75.093.3 ± 79.5
TNF-alpha (ng/mL)33.4 ± 193.0−6.3 ± 62.93.2 ± 78.7−21.3 ± 14.0−27.4 ± 10.1
Vitamin D 16.9 ± 17.323 ± 3016.2 ± 21.034.9 ± 38.529 ± 26.5
Total testosterone434.7 ± 147.4462 ± 268474 ± 277442 ± 260688 ± 204
Parathormone38.6 ± 7.749.0 ± 25.749.9 ± 28.947.7 ± 20.647.0 ± 15.1
Osteocalcin (μg/L) 14.8 ± 5.54.2 ± 2.84.6 ± 3.03.6 ± 2.37.9 ± 5.7
Calcitonin9.0 ± 2.06.3 ± 3.16.0 ± 2.66.9 ± 3.96.3 ± 2.8
Calcium9.3 ± 0.38.3 ± 0.68.3 ± 0.7§8.3 ± 0.6§9.0 ± 0.4
Phosphorus2.9 ± 0.43.1 ± 0.82.9 ± 0.73.5 ± 0.83.2 ± 0.7
Urinary calcium89.2 ± 57.7165 ± 100162 ± 96172 ± 109130 ± 83
Urinary phosphorus757 ± 873649 ± 432629 ± 435681 ± 440533 ± 384
T33.2 ± 0.72.4 ± 0.72.5 ± 0.7 2.3 ± 0.6z2.8 ± 0.7
T41.5 ± 0.31.2 ± 0.31.2 ± 0.31.3 ± 0.31.4 ± 0.2
TSH1.5 ± 0.91.2 ± 0.81.0 ± 0.6ß1.4 ± 1.0 ß1.8 ± 0.9

Data are presented as mean ± standard deviation. P < 0.001 versus controls, P < 0.01 versus controls and cirrhosis, P < 0.001 versus all others, §P < 0.001 versus group 1 and 2, zP < 0.05 versus all others, ßP < 0.05 versus controls and alcoholics.