About this Journal Submit a Manuscript Table of Contents
Gastroenterology Research and Practice
Volume 2012 (2012), Article ID 473960, 5 pages
http://dx.doi.org/10.1155/2012/473960
Clinical Study

Is Post-ERCP Pancreatitis a Genetically Predisposed Complication?

1Gastrointestinal Endoscopy Unit, Democritus University of Thrace, University General Hospital of Alexandroupolis, 68100 Dragana, Greece
2Department of Medical Laboratories, Alexandreio Technological Institute of Thessaloniki, 57400 Thessaloniki, Greece
3Department of Radiology, Democritus University of Thrace, University General Hospital of Alexandroupolis, 68100 Dragana, Greece
41st Surgical Department, Democritus University of Thrace, University General Hospital of Alexandroupolis, 68100 Dragana, Greece
5Gastroenterology Department, George Papanikolaou Hospital, 57010 Thessaloniki, Greece

Received 16 February 2012; Revised 19 June 2012; Accepted 9 July 2012

Academic Editor: Grazyna Rydzewska

Copyright © 2012 Konstantinos Mystakidis et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. S. Sherman and G. A. Lehman, “ERCP- and endoscopic sphincterotomy-induced pancreatitis,” Pancreas, vol. 6, no. 3, pp. 350–367, 1991. View at Scopus
  2. T. Mazaki, H. Masuda, and T. Takayama, “Prophylactic pancreatic stent placement and post-ERCP pancreatitis: a systematic review and meta-analysis,” Endoscopy, vol. 42, no. 10, pp. 842–852, 2010. View at Publisher · View at Google Scholar · View at Scopus
  3. E. Masci, A. Mariani, S. Curioni, and P. A. Testoni, “Risk factors for pancreatitis following endoscopic retrograde cholangiopancreatography: a meta-analysis,” Endoscopy, vol. 35, no. 10, pp. 830–834, 2003. View at Publisher · View at Google Scholar · View at Scopus
  4. M. L. Freeman and N. M. Guda, “Prevention of post-ERCP pancreatitis: a comprehensive review,” Gastrointestinal Endoscopy, vol. 59, no. 7, pp. 845–864, 2004. View at Publisher · View at Google Scholar · View at Scopus
  5. S. T. Cooper and A. Slivka, “Incidence, risk factors, and prevention of post-ERCP pancreatitis,” Gastroenterology Clinics of North America, vol. 36, no. 2, pp. 259–276, 2007. View at Publisher · View at Google Scholar · View at Scopus
  6. C. L. Cheng, S. Sherman, J. L. Watkins et al., “Risk factors for post-ERCP pancreatitis: a prospective multicenter study,” American Journal of Gastroenterology, vol. 101, no. 1, pp. 139–147, 2006. View at Publisher · View at Google Scholar · View at Scopus
  7. M. L. Freeman and N. M. Guda, “30 years of ERCP and still the same problems?” Endoscopy, vol. 39, no. 9, pp. 833–835, 2007. View at Publisher · View at Google Scholar · View at Scopus
  8. P. Wang, Z. S. Li, F. Liu et al., “Risk factors for ERCP-related complications: a prospective multicenter study,” American Journal of Gastroenterology, vol. 104, no. 1, pp. 31–40, 2009. View at Publisher · View at Google Scholar · View at Scopus
  9. P. B. Cotton, D. A. Garrow, J. Gallagher, and J. Romagnuolo, “Risk factors for complications after ERCP: a multivariate analysis of 11,497 procedures over 12 years,” Gastrointestinal Endoscopy, vol. 70, no. 1, pp. 80–88, 2009. View at Publisher · View at Google Scholar · View at Scopus
  10. P. A. Testoni, A. Mariani, A. Giussani et al., “Risk factors for post-ERCP pancreatitis in high-and low-volume centers and among expert and non-expert operators: a prospective multicenter study,” American Journal of Gastroenterology, vol. 105, no. 8, pp. 1753–1761, 2010. View at Publisher · View at Google Scholar · View at Scopus
  11. D. C. Whitcomb, M. C. Gorry, R. A. Preston et al., “Hereditary pancreatitis is caused by a mutation in the cationic trypsinogen gene,” Nature Genetics, vol. 14, no. 2, pp. 141–145, 1996. View at Publisher · View at Google Scholar · View at Scopus
  12. J. M. Chen, B. Mercier, M. P. Audrezet, and C. Ferec, “Mutational analysis of the human pancreatic secretory trypsin inhibitor (PSTI) gene in hereditary and sporadic chronic pancreatitis,” Journal of Medical Genetics, vol. 37, no. 1, pp. 67–69, 2000. View at Scopus
  13. H. Witt, W. Luck, H. C. Hennies et al., “Mutations in the gene encoding the serine protease inhibitor, Kazal type 1 are associated with chronic pancreatitis,” Nature Genetics, vol. 25, no. 2, pp. 213–216, 2000. View at Publisher · View at Google Scholar · View at Scopus
  14. R. H. Pfützer, M. M. Barmada, A. P. Brunskill et al., “SPINK1/PSTI polymorphisms act as disease modifiers in familial and idiopathic chronic pancreatitis,” Gastroenterology, vol. 119, no. 3, pp. 615–623, 2000. View at Scopus
  15. P. B. Cotton, G. Lehman, J. Vennes et al., “Endoscopic sphincterotomy complications and their management: an attempt at consensus,” Gastrointestinal Endoscopy, vol. 37, no. 3, pp. 383–393, 1991. View at Scopus
  16. J. P. H. Drenth, R. te Morsche, and J. B. Jansen, “Mutations in serine protease inhibitor Kazal type 1 are strongly associated with chronic pancreatitis,” Gut, vol. 50, no. 5, pp. 687–692, 2002. View at Publisher · View at Google Scholar · View at Scopus
  17. J. Threadgold, W. Greenhalf, I. Ellis et al., “The N34S mutation of SPINK1 (PSTI) is associated with a familial pattern of idiopathic chronic pancreatitis but does not cause the disease,” Gut, vol. 50, no. 5, pp. 675–681, 2002. View at Publisher · View at Google Scholar · View at Scopus
  18. L. Rossi, R. H. Pfützer, S. Parvin et al., “SPINK1/PSTI mutations are associated with tropical pancreatitis in Bangladesh: a preliminary report,” Pancreatology, vol. 1, no. 3, pp. 242–245, 2001. View at Publisher · View at Google Scholar · View at Scopus
  19. G. R. Chandak, M. M. Idris, D. N. Reddy, S. Bhaskar, P. V. Sriram, and L. Singh, “Mutations in the pancreatic secretory trypsin inhibitor gene (PSTI/SPINK1) rather than the cationic trypsinogen gene (PRSS1) are significantly associated with tropical calcific pancreatitis,” Journal of Medical Genetics, vol. 39, no. 5, pp. 347–351, 2002. View at Scopus
  20. Z. Hassan, V. Mohan, L. Ali et al., “SPINK1 is a susceptibility gene for fibrocalculous pancreatic diabetes in subjects from the Indian subcontinent,” American Journal of Human Genetics, vol. 71, no. 4, pp. 964–968, 2002. View at Scopus
  21. E. Bhatia, G. Choudhuri, S. S. Sikora et al., “Tropical calcific pancreatitis: strong association with SPINK1 trypsin inhibitor mutations,” Gastroenterology, vol. 123, no. 4, pp. 1020–1025, 2002. View at Publisher · View at Google Scholar · View at Scopus
  22. A. Schneider, A. Suman, L. Rossi et al., “SPINK1/PSTI mutations are associated with tropical pancreatitis and type II diabetes mellitus in Bangladesh,” Gastroenterology, vol. 123, no. 4, pp. 1026–1030, 2002. View at Publisher · View at Google Scholar · View at Scopus
  23. H. Witt, W. Luck, M. Becket et al., “Mutation in the SPINK1 trypsin inhibitor gene, alcohol use, and chronic pancreatitis,” Journal of the American Medical Association, vol. 285, no. 21, pp. 2716–2717, 2001. View at Scopus
  24. A. Schneider, R. H. Pfützer, M. M. Barmada, A. Slivka, J. Martin, and D. C. Whitcomb, “Limited contribution of the SPINK1 N34S mutation to the risk and severity of alcoholic chronic pancreatitis: a report from the United States,” Digestive Diseases and Sciences, vol. 48, no. 6, pp. 1110–1115, 2003. View at Publisher · View at Google Scholar · View at Scopus
  25. F. Perri, A. Piepoli, P. Stanziale, A. Merla, L. Zelante, and A. Andriulli, “Mutation analysis of the cystic fibrosis transmembrane conductance regulator (CFTR) gene, the cationic trypsinogen (PRSS1) gene, and the serine protease inhibitor, Kazal type 1 (SPINK1) gene in patientS with alcoholic chronic pancreatitis,” European Journal of Human Genetics, vol. 11, no. 9, pp. 687–692, 2003. View at Publisher · View at Google Scholar · View at Scopus
  26. E. Aoun, V. Muddana, G. I. Papachristou, and D. C. Whitcomb, “SPINK1 N34S is strongly associated with recurrent acute pancreatitis but is not a risk factor for the first or sentinel acute pancreatitis event,” American Journal of Gastroenterology, vol. 105, no. 2, pp. 446–451, 2010. View at Publisher · View at Google Scholar · View at Scopus
  27. M. Lempinen, U. H. Stenman, J. Halttunen, P. Puolakkainen, R. Haapiainen, and E. Kemppainen, “Early sequential changes in serum markers of acute pancreatitis induced by endoscopic retrograde cholangiopancreatography,” Pancreatology, vol. 5, no. 2-3, pp. 157–164, 2005. View at Publisher · View at Google Scholar · View at Scopus