Health-Related Quality of Life in Chinese Patients with Chronic Liver Disease

Table 3

HRQOL scores of patients with different severities of CLD (mean ± SD).

SF-36 Dimension	No cirrhosis	CA	CB	CC	Univariate aAnalysis of variance
	𝑛=186	𝑛=49	𝑛=97	𝑛=60
PF	91.7 ± 9.3^c,d	85.2 ± 17.8^c,d	72.4 ± 21.5^a,b,d	55.7 ± 25.9^a,b,c	𝑃<0.001
RP	88.2 ± 13.2^b,c,d	73.3 ± 22.2^a,c,d	61.6 ± 21.5^a,b,d	48.7 ± 25.8^a,b,c	𝑃<0.001
BP	88.5 ± 13.6^d	85.8 ± 17.4^d	83.5 ± 19.4^d	68.3 ± 25.2^a,b,c	𝑃<0.001
GH	63.5 ± 18.5^b,c,d	55.1 ± 20.1^a,c,d	35.1 ± 16.7^a,b	29.0 ± 18.3^a,b	𝑃<0.001
VT	79.0 ± 9.5^b,c,d	74.3 ± 13.1^a,d	70.8 ± 13.1^a,d	59.3 ± 20.1^a,b,c	𝑃<0.001
SF	89.1 ± 14.1^c,d	83.1 ± 18.4^c,d	66.2 ± 15.8^a,b,d	55.2 ± 25.1^a,b,c	𝑃<0.001
RE	92.4 ± 9.8^c,d	86.2 ± 15.8^d	84.6 ± 17.9^a,d	74.2 ± 26.8^a,b,c	𝑃<0.001
MH	78.4 ± 10.6^d	80.1 ± 11.3^d	79.2 ± 12.8^d	67.8 ± 21.8^a,b,c	𝑃<0.001
PCS	53.1 ± 5.9^b,c,d	48.7 ± 6.6^a,c,d	42.4 ± 7.1^a,b,d	37.2 ± 8.9^a,b,c	𝑃<0.001
MCS	53.2 ± 4.8^d	52.7 ± 6.5^d	51.8 ± 7.5^d	46.8 ± 7.5^a,b,c	𝑃<0.001

Mean age = 53.83, mean educational level = 11.19. CLD: chronic liver disease, CA: cirrhosis Class A, CB: cirrhosis Class B, CC: cirrhosis Class C, PF: physical function, RP: physical roles, BP: bodily pain, GH: general health, VT: vitality, SF: social roles, RE: emotional roles, MH: mental health, PCS: physical component summary, MCS: mental component summary, SF-36: 36-item short form. Pairwise comparisons: ^a𝑃<0.05 versus no cirrhosis, ^b𝑃<0.05 versus CA, ^c𝑃<0.05 versus CB, ^d𝑃<0.05 versus CC.