Confocal Laser Endomicroscopy in the Study of Colonic Mucosa in IBD Patients: A Review

Figure 1

p-CLE fluorescein sodium 10% imaging of the normal colon showing hexagonal, honeycomb appearance with a regular-ordered network of capillaries demarcating the luminal crypt orifice. Surface crypt architecture was classically represented by ordered and regular crypt orifices covered by a homogeneous epithelial layer with visible “black-hole” goblet cells within the subcellular matrix.