Research Article
Pantoprazole before Endoscopy in Patients with Gastroduodenal Ulcer Bleeding: Does the duration of Infusion and Ulcer Location Influence the Effects?
Table 1
Characteristics of 333 gastroduodenal ulcer bleeding patients included in the retrospective analysis.
| Characteristic | Pantoprazole () | Saline () | P value |
| Age—year | 63.4 ± 15.2 | 66.0 ± 13.4 | 0.12 |
| Male sex—number (%) | 175 (72.9%) | 59 (63.4%) | 0.08 |
| Hemoglobin—g/dL | 95.3 ± 30.1 | 96.8 ± 30.4 | 0.68 |
| Shock symptoms—number of patient (%) | 22 (9.2%) | 3 (3.2%) | 0.06 |
| Coexisting illness—number of patients (%) | | | | Cirrhosis | 40 (16.6%) | 16 (17.2%) | 0.90 | Cardiovascular | 146 (60.8%) | 58 (62.3%) | 0.79 |
| Helicobacter pylori infection—number of patients (%) | 73 (30.4%) | 33 (35.4%) | 0.37 |
| Risk factors for bleeding—number of patients (%) | | | | NSAID and/or aspirin | 120 (50.0%) | 42 (45.2%) | 0.42 | Anticoagulant | 19 (7.9%) | 8 (8.6%) | 0.83 | Previous gastroduodenal ulcer | 74 (30.8%) | 28 (30.1%) | 0.89 |
| Source of bleeding | | | | Duodenal ulcer | 128 (53.3%) | 47 (50.5%) | 0.64 | Gastric ulcer | 112 (46.7%) | 46 (49.5%) | 0.64 |
| Symptom at presentation—number of patients (%) | | | | Melena | 177 (73.7%) | 65 (69.9%) | 0.47 | Hematemesis | 111 (46.2%) | 36 (38.7%) | 0.21 | Both | 60 (25.0%) | 16 (17.2%) | 0.12 |
| Duration of infusion before endoscopy (hours) | 6.9 ± 13.2 | 5.45 ± 12.9 | 0.29 |
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