Table 2: Outcomes with different durations of pantoprazole infusion compared to saline infusion for the total of 333 gastroduodenal ulcer bleeders.

Outcome (all ulcer bleeders)Saline Pantoprazole all Pantoprazole 0–4 hrs Pantoprazole >4 hrs Pantoprazole >6 hrs
( )P value( )P value( )P value( )P value
Number of pts. (%)Number of pts. (%)Number of pts. (%)Number of pts. (%)

Endoscopic signs of bleeding
 Active bleeding 23 (24.7%)46 (19.2%)0.2632 (22.5%)0.6914 (14.3%)0.0712 (14.6%)0.09
 Nonbleeding visible vessel 18 (19.3%)49 (20.4%)0.8329 (20.4%)0.8420 (20.4%)0.8619 (23.2%)0.54
 Clot 12 (12.9%)52 (21.7%)0.5036 (25.3%)0.0216 (16.3%)0.5014 (27.1%)0.44
 Pigmented spot and clean base 40 (43.0%)93 (38.8%)0.4845 (31.6%)0.0848 (48.9%)0.4137 (45.1%)0.78
Urgent endoscopy8 (8.6%)19 (7.9%)0.8912 (8.4%)0.917 (7.1%)0.845 (6.1%)0.64
Recurrent bleeding 13 (13.9%)40 (16.7%)0.5521 (14.8%)0.8619 (19.4%)0.3217 (20.1%)0.24
Emergency surgery 10 (10.7%)21 (8.8%)0.5713 (9.2%)0.688 (8.2%)0.547 (8.5%)0.62
Mortality4 (4.3%)15 (6.3%)0.498 (5.6%)0.657 (7.1%)0.395 (6.1%)0.59

P values were calculated for comparison between saline infusion group and pantoprazole infusion group patients with different durations of pantoprazole administration.