Pantoprazole before Endoscopy in Patients with Gastroduodenal Ulcer Bleeding: Does the duration of Infusion and Ulcer Location Influence the Effects?
Table 4
Outcomes for the 158 gastric ulcer bleeders with different durations of pantoparazole infusion compared to saline infusion.
Outcome (gastric ulcer bleeders)
Saline
Pantoprazole all
Pantoprazole 0–4 hrs
Pantoprazole >4 hrs
Pantoprazole >6 hrs
()
()
P value
()
P value
()
P value
()
P value
Number of pts. (%)
Number of pts. (%)
Number of pts. (%)
Number of pts. (%)
Endoscopic signs of bleeding from duodenal ulcers
Active bleeding
9 (19.5%)
15 (13.4%)
0.32
13 (20.0%)
0.95
2 (4.3%)
0.02
2 (5.0%)
0.04
Nonbleeding visible vessel
11 (23.9%)
22 (19.6%)
0.55
12 (18.5%)
0.48
10 (21.3%)
0.76
10 (25.0%)
0.91
Clot
5 (10.9%)
28 (25.0%)
0.04
20 (30.8%)
0.01
8 (17.0%)
0.39
6 (15.0%)
0.57
Pigmented spot and clean base
21 (45.6%)
47 (41.9%)
0.67
20 (30.8%)
0.11
27 (57.4%)
0.26
22 (55.0%)
0.39
Urgent endoscopy
3 (6.5%)
8 (7.1%)
0.82
3 (4.6%)
0.54
5 (10.6%)
0.75
3 (7.5%)
0.65
Recurrent bleeding
4 (8.7%)
18 (16.1%)
0.22
10 (15.4%)
0.29
8 (17.0%)
0.23
7 (17.5%)
0.22
Emergency surgery
2 (4.3%)
6 (5.3%)
0.79
5 (7.7%)
0.48
1 (2.1%)
0.54
1 (2.5%)
0.64
Mortality
1 (2.2%)
8 (7.1%)
0.22
3 (4.6%)
0.49
5 (10.6%)
0.09
4 (10.0%)
0.12
P values were calculated for comparison between saline infusion group and pantoprazole infusion group patients with different durations of pantoprazole administration.
