Research Article
Bifidobacterium animalis ssp. lactis 420 Protects against Indomethacin-Induced Gastric Permeability in Rats
Table 5
Effect of Bifidobacterium lactis 420 cell-free extract and lactic acid against indomethacin-induced side effects.
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aThe treatment groups were a control group, an indomethacin-challenged group (NSAID), and groups supplemented daily with 1010 colony forming units of Bifidobacterium lactis B420 (live cells), B. lactis 420 cell-free extract (cell-free extract), or lactic acid for seven days prior to indomethacin challenge. bSucrose measures gastric permeability and the Lactulose : mannitol-ratio reflects small-intestinal permeability. cTDA stands for total damaged area. d-hSignificant (ANOVA; P < 0.05) differences between treatment groups are denoted pair wise by superscript letters. |