Table 5: Impact of quantitative prognostic indicators and clinical variables on pulmonary adverse events in 147 consecutive patients.

PulmonaryPulmonary
Events I–IVEvents I–IV
Univariate analysisMultivariate analysis
Yes N = 14No N = 133P value*/OR (95% CI)Odds ratioP value

Gender
 Male6620.7884NT**
 Female8711.2 (0.4, 3.5)
Age
 ≤50 year7650.9360NT
 >50 year7681.0 (0.3, 2.9)
Location
 Appendix131221.0000NT
 Colorectal 1 110.9 (0.1, 7.1)
Grade
 Grade 14570.3021NT
 Grade 2–410761.9 (0.6, 6.3)
Prior surgical score
 0–2131201.0000NT
 3–51130.7 (0.1, 5.9)
Peritoneal cancer index (4 groups)
 0–10130referenceNT
 11–204360.3779
3.3 (0.4, 31.4)
 21–305480.4060
3.1 (0.3, 28.1)
 31–394190.1512
6.3 (0.7, 60.9)
Peritoneal cancer index (2 groups A)
 0–205660.3218NT
 21+9671.8 (0.6, 5.6)
Peritoneal cancer index (2 groups B)
 0–30101140.2359NT
 31+4192.4 (0.7, 8.4)
Completeness of cytoreduction
 Complete101150.2273NT
 Incomplete4182.6 (0.7, 9.0)
Peritonectomy procedure
 Pelvic131100.4679NT
0.4 (0.1, 2.9)
 Right upper quadrant11981.0000NT
0.8 (0.2, 2.9)
 Left upper quadrant8640.5206NT
0.7 (0.2, 2.1)
 Omental bursa10600.0608NT
0.3 (0.1, 1.1)
 Anterior abd. wall6440.5553NT
0.7 (0.2, 2.0)
Peritonectomy procedure per patient
 0–23520.1938NT
 3–511812.4 (0.6, 8.8)
Visceral resections performed
 Omentectomy141301.0000NT
NC**
 Splenectomy11730.0885NT
0.3 (0.1, 1.2)
 Rectosigmoid colon7500.3648 NT
0.6 (0.2, 1.8)
 Right colon resection7630.8512 NT
0.9 (0.3, 2.7)
 Hysterectomy4431.0000 NT
1.2 (0.4, 4.0)
 Small bowel resection2270.7375 NT
1.5 (0.3, 7.2)
 Transverse colon resection3170.4078 NT
0.5 (0.1, 2.1)
 Gastrectomy041.0000 NT
NC
Visceral resections performed per patient
 0–25510.8471 NT
 3–79821.1 (0.4, 3.5)
Anastomoses performed
 Esophagojejunal021.0000NT
NC
 Small bowel1210.6945NT
2.4 (0.3, 19.6)
 Ileocolic1280.3038NT
3.5 (0.4, 27.6)
 Colocolic031.0000NT
NC
 Colorectal5510.8471 NT
1.1 (0.4, 3.5)
Anastomoses performed per patient
 0–2141251.0000 NT
 3–508NC
Ostomies performed
 None995reference
 Diverting ileostomy3270.7305NT
1.2 (0.3, 4.6)
 End ileostomy2110.3518NT
1.9 (0.4, 10.0)
Blood replacement
 None534reference
 Blood 1–32660.0966NT
0.2 (0.04, 1.1)
 Blood 4–64311.0000NT
0.9 (0.2, 3.6)
 Blood >6320.034910.2 (1.4, 76.9)0.0030
10.2 (1.4, 76.9)
Blood replacement
 Blood 0–611131Reference
 Blood >6320.0062
17.9 (2.7,118.5)
Fresh frozen plasma replacement
 None773reference
 Plasma 1–44471.0000NT
0.9 (0.2, 3.2)
 Plasma >43130.3627NT
2.4 (0.6, 10.5)
Time in operating room (hours)
 0–6010Reference
 7–12121120.5986NT
NC
 >122110.4862NT
NC
Chemotherapy treatment
 HIPEC only5740.2128NT
 HIPEC plus EPIC8572.1 (0.6, 6.7)
 Unknown21

*Pearson Chi-square or Fisher's exact test if sparse distribution.
**NC means not calculated due to 0 count in any of the cells.
***NT means not tested in multivariate modeling due to nonsignificant univariate test.