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| Marsh-Oberhuber classification | |
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| (i) Marsh I: infiltrative lesion, normal villous architecture and mucosa, and IEL increase (>30–40 lymphocytes/enterocytes counted). | |
| (ii) Marsh II: hyperplasic lesion; similar to Marsh I with crypt hyperplasia. | |
| (iii) Marsh III: destructive lesion, subdivided to the following: | |
| (a) partial villous atrophy, | |
| (b) subtotal villous atrophy, | |
| (c) total villous atrophy. | |
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| New grading system | |
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| (i) Grade A (nonatrophic): >25 IELs/100 enterocytes. | |
| (ii) Grade B (atrophic): villous-crypt ratio <3 : 1. | |
| (iii) Grade B2 (atrophic): no detectable villi. | |
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