Clinical Study
Association Analysis of ULK1 with Crohn’s Disease in a New Zealand Population
Table 2
Genotype and allele counts (and frequencies) in CD patients and in controls.
| | SNP | | Case | Control | | Case | Control | OR (955 CI) | |
| | rs10902469 | G/G | 367 (90.8) | 544 (0.86) | G | 771 (95.4) | 1177 (92.5) | 1.69 (1.14–2.50) | 0.0084* | | C/G | 37 (9.2) | 89 (0.14) | C | 37 (4.6) | 95 (7.5) | | | | C/C | 0 (0.00) | 3 (0.00) | | | | | | | rs7953348 | T/T | 276 (69.0) | 406 (65.8) | T | 663 (82.9) | 993 (80.5) | 1.17 (0.93–1.46) | 0.17 | | C/T | 111 (27.8) | 181 (29.3) | C | 137 (17.1) | 241 (19.5) | | | | C/C | 13 (3.3) | 30 (4.9) | | | | | | | rs7488085 | T/T | 355 (87.7) | 529 (82.8) | T | 759 (93.7) | 1164 (91.1) | 1.46 (1.03–2.06) | 0.030* | | C/T | 49 (12.1) | 106 (16.6) | C | 51 (6.3) | 114 (8.9) | | | | C/C | 1 (0.2) | 4 (0.6) | | | | | | | rs11616018 | T/T | 281 (70.6) | 419 (66.3) | T | 668 (83.9) | 1022 (80.9) | 1.23 (0.98–1.55) | 0.078 | | C/T | 106 (26.6) | 184 (29.1) | C | 128 (16.1) | 242 (19.1) | | | | C/C | 11 (2.8) | 29 (4.6) | | | | | | | rs12303764 | T/T | 165 (40.8) | 254 (40.3) | T | 515 (63.7) | 788 (62.5) | 1.06 (0.88–1.26) | 0.58 | | G/T | 185 (45.8) | 280 (44.4) | G | 293 (36.3) | 472 (37.5) | | | | G/G | 54 (13.4) | 96 (15.2) | | | | | | | rs3088051 | T/T | 193 (47.7) | 331 (52.2) | T | 560 (69.1) | 921 (72.6) | 1.20 (0.99–1.46) | 0.086 | | C/T | 174 (43.0) | 259 (40.9) | C | 250 (30.9) | 347 (27.4) | | | | C/C | 38 (9.4) | 44 (6.9) | | | | | | | rs3923716 | C/C | 333 (82.4) | 506 (79.9) | C | 735 (91.0) | 1134 (89.6) | 1.17 (0.86–1.59) | 0.30 | | A/C | 69 (17.1) | 122 (19.3) | A | 173 (9.0) | 132 (10.4) | | | | A/A | 2 (0.5) | 5 (0.8) | | | | | |
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*Remain statistically significant after applying a multiple testing correction using FDR.
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