Review Article
The Association between Obesity and Colorectal Cancer
Table 1
Obesity and risk of developing colon cancer.
| Study | Study type | Population | | CRC risk obese versus nonobese | Conclusion |
| Dai et al. 2007 [15] | Meta-analysis | International | 6,458 | RR 1.37 for males | Obese men have increased risk of CRC |
|
Polednak 2008 [7] | Meta-analysis | American | 153,760 | RR 1.4 for males RR 1.1 for females | Obese men have greater risk of CRC |
| Harriss et al. 2009 [8] | Meta-analysis | International | 67,361 | RR 1.24 for males RR 1.09 for females | Higher BMI increases risk of colon cancer. Men have greater risk than women. |
| Pischon et al. 2006 [16] | Prospective cohort | European | 368,277 | RR 1.55 for males RR 1.06 for females | Obese men have greater risk of CRC |
|
Rapp et al. 2005 [17] | Prospective cohort | Austrian | 145,000 | HR 1.56 for males and colon cancer | Obese men have greater risk of CRC. Obese womens have greater risk of colon cancer relative to rectal cancer. | HR 1.11 for females and colon cancer | HR 1.66 for males and rectal cancer | HR 0.66 for females and rectal cancer |
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RR: relative risk. HR: hazard ratio.
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