The Association between Obesity and Colorectal Cancer

Table 2

Obesity and oncologic outcomes after CRC surgery.

Study	Study type	Population	𝑁	Obese versus nonobese CRC patients	Conclusion
Healy et al. 2010 [19]	Retrospective cohort	British	414	No difference, 5-year survival 60% both groups	Class I obese CRC patients have similar survival rates compared to nonobese CRC patients
Sinicrope et al. 2010 [23]	Randomized controlled Trial	American	4,381	Survival difference, Class I obese women HR 1.24 versus nonobese, women	Overall CRC survival is influenced by BMI and Gender.
				Survival difference, Class II/III obese men HR 1.35 versus nonobese men
Ballian et al. 2010 [24]	Retrospective cohort	American	254	Similar disease-free survival rates at 2 years postop (85% for obese and 76% for nonobese)	Obese rectal cancer patients have similar disease-free survival rates compared to nonobese rectal cancer patients
Singh et al. 2011 [25]	Retrospective cohort	British	234	Similar disease recurrence rates (8% for both obese and nonobese patients)	Obese CRC patients have similar disease recurrence rates compared to nonobese CRC patients
Yamamoto et al. 2012 [26]	Retrospective cohort	Japanese	273	Similar recurrence-free survival and overall survival after 72 months	Obese CRC patients have similar survival rates compared to nonobese CRC patients