Table 2: Univariate analysis of clinical factors associated with grade 4 postoperative morbidity in 34 patients treated with cytoreductive surgery and HIPEC with melphalan.

Clinical variable Grade 4 morbidity value
YesNo

Dose of melphalan0.01
 50 mg/m20
 60 mg/m20
 70 mg/m24
Number of peritonectomies<0.001
 ≤21
 >25
Number of visceral resections0.002
 ≤20
 >26
Peritoneal cancer index0.38
 ≤201
 >205
EPIC0.13
 Yes2
 No26