Table 1: Characteristics of the reports of the literature regarding the portal vein thrombosis in inflammatory bowel disease.

Author No. of patients (IBD) Biochemical risk factors for PVT Therapy Outcome Maconi 8 (6 CD; 2 UC) (i) Lupus anticoagulant (1)   (ii) Increased von Willebrand factor (2) (iii) Increased homocysteine levels (4 with mutation of MTHFR-677-3 Ht) Anticoagulant (4) Recanalization Lefevre 1 (UC) Ht for prothrombin-G20210A mutation Oral anticoagulant Recanalization Jackson 3 (1 UC; 2 CD) Lupus anticoagulant + Ht for factor V Leiden mutation (1 pt) Oral anticoagulant NA Ibele 1 (UC) None Oral anticoagulant Recanalization Di Fabio 1 (CD) None Thrombobectomy + oral anticoagulant Recanalization Aguas 1 (CD) None Heparin Recanalization Palkovist 1 (UD) None LMWH Portal cavernoma Latzman 1 (CD) Ht for prothrombin-G20210A mutaion Thrombobectomy + oral anticoagulant Recanalization Hatoum 3 (CD) Factor V Leiden mutation (1) LMWH + oral anticoagulant (1 pt) Recanalization Shaked 1 (CD) None Heparin + oral anticoagulant Recanalization Guglielmi 1 (CD) None Thrombolysis + LMWH Recanalization Verna 1 (UC) Elevated FVII No therapy Atrophy of left hepatic lobe Mijnhout 1 (CD) 1 (CD) Heparin + oral anticoagulant Recanalization Fichera 4 (1 CD, 3 UC) Ht for prothrombin-G20210A mutation Oral anticoagulant Recanalization Remzi 41 (26 UC, 15 IC) NA Anticoagulation (8 pts) Recanalization (5/13 pts) Portal cavernoma (1/13 pt) No change (7/13 pts) Hagimoto 1 (UC) NA Thrombolysis + oral anticoagulant Recanalization Schafer 1 (CD) None Thrombolysis Recanalization Farkas 1 (UC) None Oral anticoagulant Recanalization Tsujikawa 1 (CD) None Thrombolysis + heparin + oral anticoagulant Recanalization Tung 1 (CD) None LMWH Recanalization Miyazaki 1 (UC) None Thrombolysis + oral anticoagulant Recanalization Irving 4 (CD) None LMWH + oral anticoagulant Recanalization Mathieu 1 (CD) Acquired protein C deficiency LMWH Recanalization Crowe 1 (CD) None Oral anticoagulant Recanalization Brinberg 1 (CD) None Heparin Recanalization

Ht: heterozygosis, LMWH: low molecular weight heparin, IC: indeterminate colitis, UC: ulcerative colitis, CD: Crohn’s disease, and MTHFR: methyl-tetrahydrofolate reductase.