Disposition Kinetics of Taxanes in Peritoneal Dissemination

<table>Time courses of docetaxel concentration in plasma, ascetic fluid, solid cancer, and suspended free cancer cells after an i.v. or i.p. injection of Taxotere in MKN-45P gastric cancer-bearing mice [<a href="/journals/grp/2012/963403/#B18">17</a>]. Taxotere (8 mg/kg) was i.v. (open symbols) or i.p. (closed symbols) injected into cancer-bearing mice on day 21 after i.p. inoculation of 10<sup>7</sup> MKN-45P gastric cancer cells. Each point with bar represents the mean ± SD of three mice. *Significantly different from i.v. injection at <svg height="11.375" id="M4" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 58.712502 11.375" width="58.712502" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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Gastroenterology Research and Practice

Disposition Kinetics of Taxanes in Peritoneal Dissemination

Figure 6