Table 1: The values of AUC of paclitaxel and docetaxel in plasma and ascitic fluid after an i.p. infusion of Taxol and Taxotere in patients with peritoneal tumor [7].

AUCpAUCaRatio of
 (mg*hr/L)(mg*hr/L)AUCa/AUCp

Paclitaxel 120 mg2.57 ± 1.431,298 ± 238505
180 mg 1.30 ± 0.862,214 ± 1281705

Docetaxel 60 mg6.65 ± 3.75370 ± 8756
80 mg 2.27 ± 0.65238 ± 24105 

The value of AUC was calculated from 0 to 25 h including the period of the infusion administration.
Each value represents the mean ± SE of three patients.
*Significantly different from Taxotere at P < 0.01.