Table 1: The values of AUC of paclitaxel and docetaxel in plasma and ascitic fluid after an i.p. infusion of Taxol and Taxotere in patients with peritoneal tumor [7].

AUCp AUCa Ratio of 　 (mg*hr/L) (mg*hr/L) AUCa/AUCp Paclitaxel　 120 mg 2.57 ± 1.43 1,298 ± 238 505 180 mg　 1.30 ± 0.86 2,214 ± 128 1705 Docetaxel　 60 mg 6.65 ± 3.75 370 ± 87 56 80 mg　 2.27 ± 0.65 238 ± 24 105

The value of AUC was calculated from 0 to 25 h including the period of the infusion administration. Each value represents the mean ± SE of three patients. *Significantly different from Taxotere at P < 0.01.