|Table 3: Pharmacokinetic parameters of paclitaxel (PAC) and docetaxel (DOC) in plasma and ascitic fluid after an i.p. administration of drugs in crEL or PS-80 to nontumor rats .|
|The value of AUC was calculated from 0 to 24 h after an i.p. administration of 40 mg/kg of each drug.|
ka: the apparent first-order absorption rate constant from the peritoneal cavity.
Each value represents the mean ± SD of three rats.
*Significantly different from DOC in 1.5% PS-80 at .