Regulation Effect of Zinc Fingers and Homeoboxes 2 on Alpha-Fetoprotein in Human Hepatocellular Carcinoma

Table 3

Relationship between NF-YA mRNA expression and clinicopathological parameters in HCC tissues.

Parameter	+ (%)	NF-YA mRNA; 𝑃 value	OR (95% CI)
Total	27 (42.9)
AFP (μg/L)
<20	10 (76.9)	.005	.16 (.04–.64)
>20	17 (34)
Tumor size (cm)
≤5	7 (38.9)	.69	1.26 (.41–3.84)
>5	20 (44.4)
Background liver
Without cirrhosis	15 (48.4)	.38	.64 (.23–1.75)
With cirrhosis	12 (37.5)
Grade
I-II	16 (37.2)	.18	2.06 (.70–6.05)
III-IV	11 (55)
Metastasis
Without	18 (51.4)	.27	.56 (.20–1.57)
With	9 (32.1)

CI: confidence interval, HCC: hepatocellular carcinoma, NF-Y: nuclear factor-Y, and OR: odds ratio.