Expression Profiling of Proliferation and Apoptotic Markers along the Adenoma-Carcinoma Sequence in Familial Adenomatous Polyposis Patients

Figure 1

Immunohistochemical stained microphotographs of sections staining for beta-catenin in nonneoplastic mucosa (a), adenoma (b), and adenocarcinoma (c); Ki-67 in nonneoplastic mucosa (d), adenoma (e), and adenocarcinoma (f); p53 in non-neoplastic mucosa (g), adenoma (h), and adenocarcinoma (i); bcl-2 in nonneoplastic mucosa (j), adenoma (k), and adenocarcinoma (l); cyclin-D1 in nonneoplastic mucosa (m), adenoma (n), and adenocarcinoma (o); caspase-3 in nonneoplastic mucosa (p), adenoma (q), and adenocarcinoma (r); CD10 in nonneoplastic mucosa (s), adenoma (t), and adenocarcinoma (u). (a, d, g, j, m, p, and s at 100x magnification; b, c, e, f, h, i, k, l, n, o, q, r, t, and u at 200x magnification).

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