124530.fig.004a
(a)
124530.fig.004b
(b)
124530.fig.004c
(c)
124530.fig.004d
(d)
124530.fig.004e
(e)
124530.fig.004f
(f)
Figure 4: Collagen deposition in the colon and lung of the normal and UC rats (Masson’s trichrome stain, × 40). (a) and (d) The intestinal mucosa and bronchia of the normal rats, only a small amount of collagen tissue. (b) and (e) After TNBS-ethanol enema, collagen fibers increased more than normal group, accompanied with red blood cell exudation and bronchial smooth muscle proliferation. (c) and (f) Four weeks later, a large number of collagen fibers proliferated, even replaced the normal mucosa and glands in the colon and lung tissue.