The Hippo-Yes Association Protein Pathway in Liver Cancer

Table 1

Summary of YAP activation in different human digestive system cancers.

Tissue type	Tissue subtype	Negative (%)	Positive (%)
Liver	Normal liver	91	9
		95	5
	HCC	38	62
		46	54
Esophagus	Normal esophagus	61	39
	Adenocarcinoma	54	46
	Metastatic disease	62	38
Colon	Normal colon	67	33
	Neoplastic colon	14	86
Stomach	Normal stomach	86	14
	Gastric adenocarcinoma	70	30
	Gastric metastatic disease	65	35