Expression and Significances of Contactin-1 in Human Gastric Cancer
Table 4
Combined expressions of VEGF-C and CNTN-1 associated with clinicopathologic characteristics (/%).
Characteristic
Both high expressiona ()
Both non high expressionb ()
value
Age (ys)
0.761
≧60
16/61.5
12/66.7
<60
10/38.5
6/33.3
Gender
0.323
Male
20/76.9
11/61.1
Female
6/23.1
7/38.9
Tumor size
0.234
≧5 cm
17/65.4
8/47.1
<5 cm
9/34.6
9/52.9
Tumor location
0.292
Upper
10/38.4
3/16.7
Middle
8/30.8
7/38.9
Lower
8/30.8
8/44.4
Lauren’s classification
0.395
Intestinal
14/53.8
12/66.7
Diffuse
12/46.2
6/33.3
TNM stage
0.023
I + II
5/19.2
10/55.6
III + IV
21/80.8
8/44.4
Vascular invasion
0.325
(+)
15/57.7
13/72.2
(−)
11/42.3
5/27.8
Serosa invasion
0.014
(+)
9/34.6
13/72.2
(−)
17/63.4
5/27.8
Lymphatic invasion
0.005
(+)
25/96.2
11/61.1
(−)
1/3.8
7/38.9
Lymph node metastasis
0.013
(+)
25/96.2
12/66.7
(−)
1/3.8
6/33.3
Lymph node metastatic ratio
0.395
≧20%
12/46.2
6/33.3
<20%
14/53.8
12/66.7
Average survival (mean ± SD) (months)
16.8 ± 3.8
23.2 ± 5.0
0.032
Note: “a”: indicates that expression of both VEGF-C and CNTN-1 in tumor cells is
high. “b”: indicates samples with combined expressions of VEGF-C and CNTN-1 except those of both high expressions.
