Table 1: Demographic, clinical characteristics and treatment of patients with Klebsiella pneumoniae liver abscesses from case reports.

Case Age SexRaceUnderlying diseasesSymptomLocation of medical therapyOutcome Reference

164FFilipinoDiabetes mellitus thrombocytosisFever, rigors, nausea, and myalgias Right lobePiperacilin-tazobactam (3.37 g Q6h) + gentamicin (400 mg qd), ceftriaxone (2 g iv qd) + oralmetronidazole (500 mg iv four times daily) followed by levofloxacin and metronidazole for 4 wks Survived [7]
271 MCaucasian Coronary artery diseaseFever, abdominal pain, and hypotension Left lobeCefotetan (2 g BID) + oral levofloxacin (500 mg qd) for 8 wks Survived [7]
353 MCaucasianMitral valve prolapse and hypercholesterolemiaFever, rigors, fatigue, malaise, night sweats, and tooth pain Left lobeCeftriaxone + metronidazole for 4 wks, gentamicin for 2 wks, followed by oral ciprofloxacin for 1 month Survived [7]
464 FFilipinoPeptic ulcer disease, coronary artery disease, and hypertensionFever, right abdominal pain, and anorexia Left lobeCiprofloxacin (400 mg, iv, bid) + metronidazole (500 mg iv, tid), followed by oral ciprofloxacin + metronidazole for 6 wksSurvived [7]
556MFilipinoNoneFever, chills, night sweats, epigastric pain, and nausea Right lobePiperacillin/tazobactam (q6h) + metronidazole (500 mg, q8h), gentamicin (180 mg, q18h), followed by oral levofloxacin (500 mg, qd) + metronidazole (500 mg, tid) for 6 wksSurvived [7]
659FFilipinoDiabetes mellitusFever, chills, anorexia, and fatigueLeft lobePiperacillin/tazobactam (3.375 g, q6h) + metronidazole (500 mg, q8h), ceftriaxone (2 g/day) + metronidazole (500 mg, q8h) for 4 wks, followed by oral levofloxacin (500 mg/day) for 3 monthsSurvived [7]
755MArgentinianNoneFever and fatigue NRCeftriaxone + metronidazole, followed by oral ciprofloxacin for 6 wks, percutaneous drainageSurvived [26]
847FOmaniNoneFever, chills, rigors, mild cough, poor oral intake, and inability to walk Right lobeAugmentin (2 g iv q6h)+ gentamicin (1.7 g IV q8h) for 3 wks, catheter drainage Survived [18]
958 FOmaniDiabetes millitusFever, malaise, and nausea Right lobeAmikacin (1 g IV q12h) + ceftazidime (1.5 g IV q8h for 5 days), followed by ciprofloxacin (0.5 g IV q12h for 12 days) and piperacillin/tazobactam (4.5 g iv q8h) for 15 days Survived [18]
1062 MIrishPeripheral vascular disease and excess alcohol intake Abdominal pain, anorexia and nauseaNRPiperacillin/tazobactam (4.5 g iv q8h) for 15 days Survived [14]
1140MFilipinoDiabetes mellitus Fever, polydipsia, and polyuriaRight lobeCeftriaxone (2 g iv qd), oralciprofloxacin for 69 days; percutaneous drainage, intravenous gentamicin, and ciprofloxacin (400 mg, iv bid) for 5 days Survived [14]
1255MChinese Diabetes mellitus Vomiting, abdominal pain, fever, and rigors Right lobeOral ciprofloxacin for 36 days, oral cephalexin for 97 days, amoxicillin-clavulanic acid (1.2 g, iv, tid) + gentamicin (320 mg/day) + metronidazole (500 mg, iv, tid), followed by ceftriaxone (2 g/day·iv) + oral metronidazole (400 mg, bid), percutaneous drainageSurvived [14]
1358 MJapanese Diabetes mellitus Malaise Right lobeMeropenem (1 g iv q12h) for 6 days, cefmetazole (2 g iv Q8h), oral cefcapene pivoxil (100 mg, tid), and antibiotic treatment for 30 days Survived [5]
1461 FJapanese Diabetes mellitus Fever, chills, and a slight headache NRMeropenem (1 g, iv, q8h) + linezolid (600 mg, iv, q12h), changed to ceftriaxone (2 g q12h) for 20 days, followed by oral cephalexin (250 mg q6h) for 31 daysSurvived [5]
1543 MJapanese NoneRight hypochondriac and epigastric pain Right lobeMeropenem (1 g day iv) for 15 days + IV insulin, mg/day, and oral ciprofloxacin (400 mg/day) for 50 days Survived [45]

NR: not reported.