The Role of IL-6, 8, and 10, sTNFr, CRP, and Pancreatic Elastase in the Prediction of Systemic Complications in Patients with Acute Pancreatitis

Table 3

Values of biochemical parameters measured in patients without systemic complications (𝑁=122) and patients who developed systemic complications (𝑁=28) and comparison of measured values. Bold printed are the indicators with statistically significant difference.

Parameters	Patients without systemic complications (𝑁=122)	Patients with systemic complications (𝑁=28)	𝑃 value
	Median (95% CI)	Median (95% CI)
IL-6 (1st day) [pg/mL]	20 (16–34)	104 (51–139)	0.001
IL-8 (1st day) [pg/mL]	27 (19–34)	53 (33–98)	0.012
IL-10 (1st day) [pg/mL]	5.1 (2.6–8.9)	26 (8–58)	0.010
sTNFr (1st day) [pg/mL]	1520 (1220–1886)	2220 (1873–2722)	0.004
CRP (1st day) [mg/L]	14.4 (11.3–28.3)	15 (5.1–78.8)	0.954
CRP (3rd day) [mg/L]	85 (66.7–122)	216 (105–257)	0.002
Elastase (1st day) [ng/mL]	5.7 (4.2–7.5)	7.5 (3.6–10.9)	0.249
Elastase (3rd day) [ng/mL]	1.7 (1.4–1.9)	2.5 (2.1–5.1)	0.001