A Pilot Study to Investigate the Role of Thymidylate Synthase as a Marker of Prognosis for Neoadjuvant Chemotherapy in Gastric and Gastro-Oesophageal Junction Adenocarcinoma

Table 2

Clinical and histological factor associations by Fisher’s Exact test.

Characteristics	TS positive	TS negative	Fisher’s exact test
Gender
Male	30	3	0.71
Female	11	1
Tumour site
Gastric	15	2	0.49
GOJ	26	2
Differentiation
Well/moderate	19	1	0.62
Poor	22	3
T stage
T0/T1	20	2	0.68
T2/3/4	21	2
N stage
Negative	11	3	0.08
Positive	30	1
Vascular invasion
Yes	6	1	0.51
No	35	3
Lymphatic invasion
Yes	7	1	0.56
No	34	3
CRM
Negative	31	4	0.56
Positive	10	0
Histological response
Yes	3	1	0.32
No	38	3
Recurrence
No	26	3	0.55
Yes	15	1

 *Fisher’s exact test.
GOJ: gastro-oesophageal junction; CRM: circumferential resection margin.