Clinical Study

Prediction and Treatment of Difficult Cases in Colorectal Endoscopic Submucosal Dissection

Table 2

Clinical outcomes of difficult and non-difficult groups in view of procedure time.

Difficult group
(≥120 min)
Non-difficult group
(<120 min)
P value

Case numbers (%)100 (19.3%)418 (80.7%)
Tumor size (mm), mean ± SD <0.001
Tumor location (%)
 Right-sided/left-sided/rectum
43.0/18.0/39.050.2/20.2/29.6NS
Morphology (%) 
Superficial/protruding
83.0/17.080.4/19.6NS
Degree of fibrosis (%)
F0/F1/F2
28.0/48.0/24.0
(28/48/24)
59.1/34.9/6.0
(247/146/25)
<0.001
The ratio of Expert/non-expert (%) (n)37.0/63.0
(37/63)
33.7/66.3
(141/277)
NS
Procedure time (minutes), mean ± SD <0.001
En bloc resection (%)77.0 95.0<0.001
Perforation (%) (n)11.0 (11)2.2 (9)<0.001
Postoperative hemorrhage (%) (n)6.0 (6)1.4 (6)<0.01
Histology (%)
Ad/M/SM
33.0/51.0/16.047.8/40.8/11.4NS

Right-sided: from cecum to transverse colon, left-sided: from descending to sigmoid colon, F0: no fibrosis, F1: mild fibrosis, F2: severe fibrosis, Ad: adenoma, M: intramucosal cancer, SM: submucosal invaded cancer, and NS: not significant.