Indirect Comparison Showed Survival Benefit from Adjuvant Chemoradiotherapy in Completely Resected Gastric Cancer with D2 Lymphadenectomy

Table 2

Indirect comparison on the efficacy of chemoradiotherapy versus observation for resected gastric cancer after D2 lymphadenectomy.

CRT versus Obs	Number of trials; in comparison	Hazard ratio (95% CI)	𝑃 value
DFS	7	0.43 (0.33, 0.55)	0.00
	6*	0.43 (0.34, 0.56)	0.00
OS	6	0.52 (0.38, 0.71)	0.00
	5*	0.53 (0.38, 0.72)	0.00

CRT: chemoradiotherapy, Obs: observation, 95% CI: 95% confidence interval, DFS: disease-free survival, and OS: overall survival. *Subgroup analysis after omitting the trial from Spain.